While you are looking into the additive effects of the two gases, add a third. Carbon dioxide has long been a contributor to narcosis. It seems the harder you work on a dive, the greater the narcotic effect.So yes here I think this identifies where uncertainty comes up. Do the effects of ppO2 and ppN2 really just add up like that, to an easily explainable combined effect? A simple arithmetic, but what is the mechanism by which that actually works?
Individual susceptibility is also a factor. Narcosis seems to affect different people in different ways. Some feel very loopy. I personally do not feel a thing, even when my actions show I am clearly affected. Why is that? It shows how little we still know.