We babysit for some of our friend's pups when they vacation, and then they return the favor.
When they take care of are animals, they have to move into our house while we are gone because we have 3 dogs, a cat, 2 guinea pigs and 5 horses. 2 of the dogs are on meds that need to be administered every 12 hours.
We usually take care of their pups 2 or 3 times for every 1 of our trips!
We have also done trips to the pacific northwest and put the camper on the back of the truck. The dogs get a big bowl of water and hang out in the camper while we dive.