The really short, you run the highest PPO2 pratical until you reach a target PPO2 level. For basic CCR, 1.3 is normal. There are cahnges as you get more technical but for starters just run 1.3 PPO2.
When you get deeper than 1.3 PPO2 on near pure oxygen (Hard to get 100% in the loop, hard to get rid of that last little bit of inert stuff and not worth it) you add in inert gasses to keep the PPO2 at the level you want. Keep adding inert gasses (N2 and He in a fixed ratio based on the DIL fill) as you go deeper. Total partial pressures will add up to total pressure.
So it is completely possible, and happens quite often, your fast tissues will be void of normal level of N2 on the surface. Going off the loop and breathing air, you will be ongassing N2 on the surface
IF you have a Shearwater take a look at the tissue loading graph. Understand what the lines and color shifts mean. You will learn a lot of what is going on.
If you dive air dil, Get to a .79 PPN2. It will be the same nitrogen loading as breathing surface air. What depth does that happen at? Any that you get a .79 PPN2. Add the PPN2 and PPO2 numbers together, that will be the total pressure (depth) that you are at. .79 PPN2 and 1.21 PPO2 is 2.0 pressures, or about 30'. Drop some PPO2 numbers and you can still keep the PPN2 at a shallower depth.
There is no magic number depth where it always matches the surface, it is the pressure that says if it matches or not.
If you are at 0.2 PPN2 and 1.3 PPO2, you are hanging out in about 15' of water, degassing. And where the fast tissues loose almost all the dissolved Nitrogen.