Here is a quote from an article that questions the benefit of mouth to mouth respiration during CPR:
Before the rediscovery of mouth-to-mouth ventilation in the 1950s and 60s, manual techniques of ventilation were used widely for rescue breathing. The principal advantage of mouth-to-mouth ventilation is that an integral part of it is maintanence of upper airway patency. In this issue of CHEST, Fukui and coworkers (see page 1663) report that, in a rodent model of cardiac arrest, upper airway patency is important for gas exchange during chest compressions. In this model, positive pressure ventilation was not used, but ventilation did occur during spontaneous gasping and also possibly secondary to chest compression. When airway patency was protected with an oropharyngeal device, spontaneous gasping was more than twice as frequent and arterial oxygen saturation higher than without airway protection. Nevertheless, return of spontaneous circulation and 24-h survival did not differ between the two groups. The study suggests that, at least in some animals, spontaneous gasping during cardiac arrest was associated with maintenance of some upper airway tone and patency. It also shows that gasping and gas exchange are improved when airway patency is protected.
Despite any limitations in this study, how does it relate to CPR in humans? Ventilation by spontaneous gasping has some advantages over mouth-to-mouth ventilation. Compared with air, the gas given during mouth-to-mouth ventilation has much more [CO.sub.2] (4%) and less [O.sub.2] (6%), which may affect resuscitation adversely,[7] while gas inhaled during spontaneous gasping has virtually no [CO.sub2] and 21% [O.sub.2]. Mouth-to-mouth ventilation uses positive pressure, which is associated with gastric inflation, regurgitation, and aspiration; inhalation during spontaneous gasping occurs during negative upper airway pressure, which prevents gastric inflation. Finally, transmission of contagious diseases by spontaneous gasping is unlikely.
Whether humans gasp as frequently and as deeply as healthy animals during cardiac arrest and whether the upper airway remains unobstructed are unknown. Because the study by Fukui et al shows improved oxygenation and ventilation when the upper airway was patent, assuring an unobstructed airway should remain a high priority during basic life support. For now, CPR instruction should recommend that, when a victim is gasping spontaneously, if the rescuer is unwilling to perform mouth-to-mouth ventilation, then, at the very least, upper airway patency should be maintained by conventional means in addition to chest compression.[8] The study by Fukui et al is an important contribution to the growing body of medical literature on ventilation during cardiac arrest. Many questions in this crucial area, however, remain to be answered by future research.