Great question and I wish I had a highly experienced answer for you but both my attempts to dive my own coast were blow out by storms.uncfnp - being from NC how do you determine your MOD then? 1.5 or 1.4 to the sand or the deck of what you want to dive or are you diving reefs?
Most of my diving is Florida and the depths are fairly well known in advance so no real risk of getting caught on board with too hot a mix. Once I did though so I just stayed around the 1.4 MOD. Most of my Florida diving is reef and I usually stay near the top if there is a ledge but willing to briefly drop deeper. I like to know the 1.6 depth as a contingency but honestly most of the time I'd have to get out a shovel to reach this and if I did I'd make darn sure it was brief.
The problem with NC and probably NE Atlantic is not knowing a hard max depth when selecting tanks so you have to plan for at least the most likely possibilities. Plus if I'm diving NC I'll almost certainly use a deco mix, so my plan would be sand 1.4 and deco 1.6 but I know that very little of my time, if any would be sand so would not even hit 1.4 max. Hitting sand would just shorten my dive time.
My choice to set the computer at 1.5 is from my Nitrox course and if I should decide to dive after that lobster my computer won't yell at me. But IRL I very seldom hit 1.5 and then only briefly.
Edit: If I were diving NC recreational only and if it's an option, I would look at the most likely wrecks and the depth that would give me the most intesting dive and max my bottom time then plan 1.4 at that depth.