A sealed diaphragm second stage stays "cleaner" but a piston second stage in general will have a lower parts count, is more bullet proof and will offer better raw performance. I would not hesitate to use a MK 25 in water down to 50 degrees but would suggest a Mk 16 for water colder than that.
I am also a fan of the G250 over the S600. Same reg internally except the G250 has a larger diaphragm and has a better record of reliability in cold water and in general is a time tested high performance second stage. I like some of the engineering concepts behind the X650, but I don't think the design is mature yet and I think SP really screwed up discontinuing the D400 as I don't think the X650 will ever fully match it.
I am also a fan of the G250 over the S600. Same reg internally except the G250 has a larger diaphragm and has a better record of reliability in cold water and in general is a time tested high performance second stage. I like some of the engineering concepts behind the X650, but I don't think the design is mature yet and I think SP really screwed up discontinuing the D400 as I don't think the X650 will ever fully match it.