There are some great travel health websites out there, but nothing's better than talking to a travel health doc who knows your medical history. That being said, I really like
www.tripprep.com. It's a rather cautious portrayl of traveling in mostly Honduras (which is a different cultural experience than the Bay Islands it would seem), but since it combines the State Dept's consular sheet on Honduras, CDC info, and other stuff, it seems to be a comprehensive source.
I'm traveling to the Bay Islands in March and as a result, I received the following vaccines at last week's travel health appt: tetanus booster, hep A, and typhoid (oral, take 4 pills in 8 days and you're immune for 5 years - you can also get a shot which confers immunity for 2 years). I also left with a prescription for chloroquine (anti-malarial) and a high dose antibiotic (just in case of severe diarrhea caused by E coli - most likely bugger, etcetera). Chloroquine needs to be taken the week before you leave, while you're on vacation, and then for four weeks after you return. The malaria found in Honduras isn't the mostly deadly kind, but it could still be a heck of an awful experience. But even with chloroquine, it's still a good idea to cover up at night and use bug spray!
While it seems like a lot, if you plan on traveling to developing parts of the world on a fairly regular basis, getting vaccinated is probably a good idea anyway. I went to Beijing on somewhat of a whim last December and the recommendations in terms of shots were the same (I didn't get them that time and, although I was fine, I think I would have been less worried about getting a GI bug had I prepared ahead of time.)
