This is an example of a common scenario that will test the experience of your skiff driver to find and pick you up before deteriorating into a worst case lost-at-sea situation; Surfacing post-drift dive into a momentary tropical rain squall in near zero visibility:
Currently by itself, a Nautilus Lifeline GPS will not work in all lost-at-sea scenarios alone by itself; you will need as backup an additional 406Mhz PLB (Personal Locator Beacon, transmitting straight to satellite).
DSC (Digital Selective Calling) is a two way digital paging function and it is not necessarily the exclusive domain of distress alerts within the GMDSS (Global Maritime Distress Safety System) framework. For instance you can use it for station to station communication via HF or VHF frequency radio. The only way a AIS (Automatic Identification System) PLB with VHF DSC functionality could be regarded as GMDSS compliant is if it was DSC acknowledgment capable, and even then that compliance may be debatable as position may only be just AIS limited capability with a 5km range at best (depending on rain & swell height conditions). Combined functionality AIS/406Mhz PLB devices to be developed, manufactured and hopefully available sometime in the near future may change that.
The correct way (at least imho) to use DSC is to first send a mmsi (Maritime Mobile Service Identity) call to the mothership let's say repeatedly for maybe 5 minutes. if the call doesn't get acknowledged then escalate to an All Ships call hoping some good samaritan on a nearby boat is more keen to haul your sorry ass out of the water than the "mates" on the mothership, who clearly lost track and are out of VHF reception range of where you drifted off to. At the same time as the initial DSC call, the AIS MOB (Man Overboard) call goes out as well. If none of this works - let's say 10 minutes or so - a 406Mhz PLB call should go out to alert the overhead cospas/sarsat satellite system as the last resort for rescue, as clearly no local boats are going to save your ass, because they are out of range or worst case don't have even have a VHF radio at all to receive your distress signal.
Ideally such a combined AIS MOB/406Mhz PLB unit would be user programmable so you can tailor the operation to suit the kind of off-shipping lanes sailing or remote area Scuba diving you do, because otherwise a unit with only one fixed mode -such as the current Nautilus Lifeline AIS GPS VHF product- will not cover all the various kind of lost-at-sea sailing/scuba scenarios one can think of.
The last best possible hope of Rescue with current technology is always a separate 406Mhz PLB straight to satellite, over a line-of-sight limited Nautilus Lifeline VHF product.
https://www.soundingsonline.com/voices/epirb-ais-satellite