I'm not familiar with the Tusa, but can comment on the Mares MR-12 (have 3 of them, and 2 MR-22 Abyss regs).
The MR-12 is a well-established, simple, rugged design that has been around for a long time. It is now Mares' "low-end" balanced diaphragm regulator (price-wise), but this does not make it a low end regulator. The Prestige 2nd on the other hand is newer, and I don't have any experience at all with it. Mares typically uses a classic, non-adjustable "unbalanced" downstream 2nd stage, and from what I've seen (pictures only) the Prestige seems to follow this design pattern. Some (mistakenly I think) see this simpler 2nd stage design as somehow inferior to adjustable 2nds, but really this just depends on the overall design of the 2nd stage, and a lot depends on proper "tuning" of the 2nd stage.
Best wishes.