Anyway Madmole is correct;
Not quite as simple as that!
I've been talking today to someone involved in producing deco plans for 250 - 300m dives and they are amasing a load of evidence that their divers are getting bent if they swap back to Nitrox or air at 40m or so, Staying on the He doesn't do this
It would be good if "someone" had these results published for peer review in a hyperbaric physiology journal, since it runs counter to a general concensus.
Nitrogen and He do interact, its a thing called isobaric counterdiffusion
Yes, they interact. Deep tissue counterdiffusion is a very possible outcome
of switching from nitrogen to helium , particularly at a 'deeper' depth, as at shallower depths the results were less severe (Harvey 1977, Hamilton et al 1982). There are similar results in complex COMEX experiments when switching from hydreliox to heliox, BTW.
However, it is generally accepted that
divers may switch the inert gas from helium to nitrogen (Hamilton 1976, Lambertsen 1989). I note that Madmole mentions that this
causes such nasties as Vestibular bends (a bend almost exclusive to folks who swap from He to Nitrogen mixes)
Yes, this is the controversial part. Perhaps this
might have happened in some instances. Alternatively, it
could be the result of the use of an inadequate decompression table (Hamilton&Thalmann in Bennett&Elliot 2003) or perhaps even of incorrect decompression procedures?
Now, there are reports dating back to WWII of adverse effects when switching to air at 50 metres (Momsen 1942) and possible vestibular or inner ear DCS or counterdiffusion sickness when using rapid shifts deeper than 33 metres (Hamilton 1976). Hamilton & Thalmann (2003) also mention the possibility of this being the abrupt exposure to nitrogen narcosis ...
Interestingly I've been talking today to someone involved in producing deco plans for 250 - 300m dives
At dives to these extreme depths, I certainly believe a deep gas switch to air (nitrogen)
may create problems. As I've previously suggested, if nothing else for the effects of nitrogen narcosis.
From the above any budding technical diver attempting a nitrogen-rich switch should contemplate doing that at shallower depths, say from 20 metres. This is consistent with my first post, BTW:
The disadvantage, as I see it, is that if you do the switch too deep, you will end up heavily narked,
(I'm consistent you, know, there is method to the madness ...

)
Alternatively, of course, one runs with Thalmann's successful findings on heliox decompression (1985) and stays on the helium-based 'bottom mix'. Nobody actually suggests otherwise. But then preferably by paying the added decompression penalty. It's a free choice.
I'm sorry this is such a long post, but there is a tendency on many forums to run with very simple opinions and solutions decompression-wise and although I think Madmole is a fantastic resource on Inspiration diving and all-around great guy, I don't really agree offhand with all the decompression opinions expressed in his post.
Its to do with the larger nitrogen moleclules attaching to the He bubble seeds. A small He bubble is mobile and diffuses quickly, once the N attaches it alters the physical properties of the bubble.
An almost inert gas
attaching to a
truly inert gas molecule? Hmmmm ... Nope, sorry, can't buy that offhand ...
There we go, so the answer may have been incorrect after all, well I've survived on Heliox for along time, so I guess I'll stick to what works.
There is this somewhat exasperating tendency to believe (particularly on US boards) that there is a 'right' and a 'wrong' ... This post hopefully shows it's much more complicated than that. But as a conclusion, yes, if you're happy with heliox decompression, stick with it. But do try and pay the decompression price.