The majority of "don't mix and match" is marketing (vendors wanting to upsell the whole package).... As @lowwall stated, all the second stage cares about the 1st stage is that it provides air at an intermediate pressure (IP) within the range it can be adjusted to. Most modern regs have significant overlap in their IP ranges (main exception I know off hand is Poseidon at 165 psi). Where the issue can come in is aftermarket parts within a second stage having unsuspected consequences.... Like you found with the "minor" inside diameter change of the mouthpiece having a major effect on venturi.I wish this explanation had been given when I've been told to not mix second stage vendors. I now see how the two are so interdependent on being tuned to one another. I must have just got lucky that my XTX50 and 620ti both play nice with the Apex DST 1st stage (perhaps the 620Ti is suffering a little not being mated with a Scuba Pro MK 25, but I hadn't noticed)
Short version: most 1sts and 2nds can be mixed at will with no ill effects.
One last thought on that. A balanced first stage provides a stable IP throughout the supply pressure range. A balanced second stage is relatively unaffected by IP variations. There are some other minor effects involved, but that's the main point. Which means a balanced first with balanced or unbalanced second will perform the same right down until the tank is at or below IP. An unbalanced first with a balanced second will behave about the same. An unbalanced first with an unbalanced second will breath a tiny bit harder as the tank pressure drops.
Respectfully,
James