DanV
Not meaning to sound like a pessimist, but the truth very well may be that the changes you are describing could occur (and even be likely) even with the full weight of man's attempts to correct the problem. The simple truth is that we simply do not have the means to selectively harvest lionfish in an efficient manner. Sure, we can spear many of them out of favorite dive sites, but that is only an unbelieveably tiny fraction of the affected ecosystems. We simply can't go deep enough or cover enough real estate to affect anything approaching control. Breeding aggragations have been found below 300 feet (ROV documented), and let's face it...we don't even dive much of the reefs due to accessibility problems.
Simply put, man won't be the answer to this situation...at least not in the predator role. In my opinion (for what it's worth--which is not much, granted) the answer lies in another direction, such as conservation of other mid-level predators and MPA's, which give some species relief and habitat to rebound from man's predation upon them (as already noted).