Walter once bubbled...
While it's true when using DIN, there's no o-ring in the valve to replace every 500 or so dives, you do have to contend with the o-ring that falls out of the regulator every other dive.
"less hassles with...........misalignments"?
I've never heard of a hassle with a misaligned yoke, but cross threaded DIN is another story.
DIN is an improvement over yoke in giving a more secure connection, but it is a minor improvement at best and I'm not convinced it's worth the additional hassles unless you are using very high pressures. Prior to the introduction of DIN valves to recreational SCUBA in the US, I routinely used a yoke for pressures up to 3800 PSI with no failures. Most DIN tanks in the US are actually filled with an adapter that allows them to be filled with a yoke connection to pressures many consider too high for a yoke.