Lightning Fish:
I would be very critical of this article. I'm a medical researcher by profession, :doctor: and this article is quite concerning to me, for several reasons:
1) It is talking about an editorial - i.e. an opinion piece - not an actual scientific paper. Here's the original editorial:
http://bmj.bmjjournals.com/cgi/cont...INDEX=0&sortspec=relevance&resourcetype=HWCIT
2) The major criticism of the author is not the efficacy of the vaccine, but rather the way in which efficacy was demonstrated. He actually has a table in his article giving an overview of several studies, and each and every study in that table showed beneficial results after vaccination (see table 2 in the above link).
3) The types of studies which he proposes we replace current methods with are very difficult to implement, particularly with diseases like the flu. There are also ethical issues with the study method he proposes (it would actually be illegal in several countries, as it involves withholding a known effective therapeutic from people at risk).
4) There is no guarantee his method would get better results - the flu is a highly variable disease year-to-year, as is the efficacy of it's vaccine. His methodology may produce more accurate results for a single year, but would be less likely then current methods to accurately measure the efficacy of the vaccine from year-to-year.
Not to mention the study he proposes would probably have a
multi-billion dollar price tag associated with it.
5) The large majority of the scientific and medical community disagree with him, and finally
6) He works for the Cochrane group. Although this group does very excellent work, they are renound for their overly stringent criteria. Based on their standards for vaccine development, they stated that the smallpox vaccine would be categorized as having "questionable effectiveness" - and that vaccine was sufficient to wipe out smallpox world-wide. If Cochrane says something works, or is true; then it works, or is true. But if they same something may not work (which is what this study says), then it probably does work; it just doesn't achieve the perfection they seem to think all medicine should achieve.
It's like my last lady friend - nothing was ever right, no matter how close to perfect I got. :gorgeous:
Bryan