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When deciding on which GF to use, I chose Plato's synopsis on philosophy.
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Then that's likely the difference.
Hello,
Two apologies.
First, for being so late in responding to this. I have had a very busy few weeks clinically.
Second, for mislabelling the Y axis on the ISS graphs. They have been transposed between presentations so many times I had not noticed that the units were not properly defined any more.
Stuart, to your question.
You describe a somewhat hypothetical question that could not happen in reality - particularly your first dive profile. It would not be possible to have one tissue at 10 and all the others at 1 because in achieving 10 in one tissue would inevitably mean that other tissues with similar kinetics would be much closer, with a graduated change to differing values as the tissue half times diverged. Moreover comparing profiles with such divergent supersaturation patterns like the hypothetical you propose is not the intent of ISS. This is a bit similar to the argument Ross tried when suggesting that the ISS was crap because going on a ski trip at altitude would produce a total ISS similar to a dive. ISS comparisons are only useful for comparing profiles that are substantially equivalent in important respects (eg to the same depth for the same bottom time with the same total decompression time, but with different distribution of stop depths and times). It would not be a valid method of comparing two profiles that would produce the sort of wildly different patterns of supersaturation that you describe in your hypothetical.
How you actually use ISS, and the extent to which we can consider it a validated means of evaluating optimal decompression remain open to discussion, but it has been an interesting metric in comparing the profiles discussed in debates over deep vs less deep stop approaches.
Simon M
It sounds like you're ignoring partial pressures from O2, CO2, and H2O (water vapor). I don't think that's the best model. VPM itself uses the other gases in its model (e.g. look in the VPM code for "Constant_Pressure_Other_Gases"). Thalmann has also stated, "The total tissue gas burden is the sum of the inert gas burden and the tissue O2, CO2, and water vapor partial pressures."thank you, makes sense. From the Parker et.al. (1996) paper I still think that ignoring O2 in the ISS integral would be more appropriate and won't change the ranking order of the four profiles, or even result in larger differences. Do you know if in the ISS calculation for these graphs, were separate tissues used for oxygen with own half-times, or did they just add oxygen to nitrogen tissues?
It sounds like you're ignoring partial pressures from O2, CO2, and H2O (water vapor). I don't think that's the best model. VPM itself uses the other gases in its model (e.g. look in the VPM code for "Constant_Pressure_Other_Gases"). Thalmann has also stated, "The total tissue gas burden is the sum of the inert gas burden and the tissue O2, CO2, and water vapor partial pressures."
These gases are modeled as constant additions to compartment pressures, not as independent gases with half-times, etc.
Nobody has ever stated that ISS was the sole factor in determining a profile's effectiveness. As Dr. Doolette has stated, "The integral supersaturation is an “algorithm-independent” way to look at the magnitude and duration of supersaturation of a schedule prescribed by any algorithm, it is unrelated to how that schedule was prescribed."I then tried to minimize ISS and found: the shallower the better. GF150/50 is very good in terms of ISS but will almost certainly cause a hit.
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I then tried to minimize ISS and found: the shallower the better. GF150/50 is very good in terms of ISS but will almost certainly cause a hit.
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