Whew!
Lots of good, bad, and indifferent info in this thread...
Not surprising considering what we "know" about oxtox hits.
I'll qualify this list with "AFAIK" - that is, from what I've been able to glean from the available literature as "fact" - and what's floating around out there as "anecdotal evidence."
(1) As TS&M has already said, the spread on the data is positively daunting; one might say even baffling. Within the general population there is a positively tremendous variation on susceptability, and experimental data shows that even the same individual may have a very wide variance from day to day... In the one intentional high PO
2 chamber experiment I know of, subjects were exposed to pure O
2 at 3.1 ATA and held there (performing various "normal activity" tasks) until symptoms were felt or observed. Times from initial switch to oxygen to symptoms varied from 5 minutes to over 2½ hours! But even 5 minutes at 3.1 isn't "a few seconds if you exceed 1.6"...
This vast variance in susceptability is also supported from the decompression treatment oxtox incidents report already cited.
(2) The Navy's limit for surface-supplied mixed gas dives has been pulled back to 1.3 ATA.
(3) As for
confirmed cases of oxtox in the
absence of drugs, AFAIK, within the NOAA time limits, there has been one case of a hit in an individual at 1.6 ATA who had previously exceeded 1.6 ATA and then ascended back to 1.6; there have been zero cases of hits where an individual has exceeded 1.6 but safely returned to 1.4 or shallower, and there have been zero cases of hits when 1.6 has not been exceeded.
(4) There is no study (yet) validating a correlation between the use of drugs and oxtox susceptability, but there is a mounting pile of anecdotal evidence that drugs that "heighten nervousness" (pseudoephedrine is the main contender here) may lower oxygen tolerance and increase susceptability to oxtox.
(5) CO
2 levels can get high enough to cause convulsions at normal (.21ATA) oxygen levels - which one causes the convulsion is really irrelevant, eh?.
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(6) It is
my opinion that there are individuals who are "borderline epileptic" who may be susceptable to oxtox at any elevated PO
2.
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So... what do I do? And what am I willing to do?
(a) My planned MOD is based on 1.4 for bottom gasses; 1.6 for deco gasses
(b) About the only drug I'll dive with is an aspirin.
(c) If I accidentally exceed my MOD for a few seconds I don't get excited about it, just swim back up to where I'm supposed to be, and if in deco, add a backgas break.
(d) It'd have to be a mighty expensive piece of equipment to get me to go below 1.6 to retrieve it, but I ain't saying I wouldn't.
(e) If it's a lifesaving situation, I wouldn't hesitate to go to 2.0 or even more for a few seconds to retrieve someone.
(f) I try to avoid heavy work at all times, especially underwater. If I plan to do any heavy work underwater, it ain't on nitrox.

Rick