You *should* have enough, but often when things go sideways unforeseen delays and issues can pop up. The manifold gives you the opportunity to loose all your gas rather than half of it.
Back in February I had a set of doubles fall off of a bench at Ginnie. They landed on the manifold, a hefty drop to the ground. The isolation knob was mushroomed. The manifold held, I even dove it later that day.
I've never heard of a fatality due to a manifold failure, if you can cite one, I'd love to hear it.
On the other hand, close to two years ago, I was called to do the body recovery of a new sidemount diver that drowned while switching regs; he had plenty of gas in both cylinders, but one had rolled off and when he switched to it, he got no air and drowned while trying to find his other reg. Thankfully someone else did the recovery while I was en route.