I join this thread right now, and, besides any consideration than the form factor I just would prefer full size.
For sure, size does matter, and this is a fac
Seriously, if I had two identical (and almost perfect for my needs) computers, one full size and the other watch sized, I would slightly prefer the bigger - probably I am more polarized now than in the past (presbyopia) but I think that could not be completely matter of sight.
For example, and I'm sorry for that, because I have difficulties to explain it in English, I feel that Human Factor play a not negligible role in that, and it is not only for the clarity of the display and info shown on it, but also because, if it cannot be weared 24/7, will be cared of (or the opposite) as any other piece of equipment: It will stay with regulators, will be serviced in the same way and, will not be banged around when my friend will come asking to do a parachute jump or to climb that rocks, just because the sightseeing from there is breathtaking ...
Just my two cents ....
Then, because all computer are made different, my choice will be driven from the features I consider more important to me and then from the size, still recognizing that a beautiful design is something I will, at least, check once.