are a lot like used cars. Some have been well taken care of and treated well, others have been used and abused. Some will run trouble-free for years while others will die a a quick and painful death shortly after purchase.
The question I most often ask is "why is this person selling this item?" That can possibly give you some insight, if they aren't lying. Did they step up to a newer model with more features, or did they get tired of the problems with the old one. Remember that you need to have your BS-meter on full sensitivity while they answer.
Of course buying a new car or a new computer doesn't guarantee that it will work flawlessly, just that it will be under warranty.
Remember also that your life might depend upon the information you get from the computer, and how much risk do you really want to take in order to save some dollars? Only you can answer that question.