First, if you put a dive with lets say 15minutes bottomtime at 100m depth in your decoplanner, you will see that there is almost no difference in divetime when using an 80% or an 100%.
And you will see that the CNS loading is almost half when using 80% over 100%.
So if you find cns loading important, then choose the 80%
But then, if you read 1 of the explanations of oxygen window, then it means how bigger the gradient between tissueloading and the gas you are breathing, the faster offgassing is. That means oxygen is more efficient than 80%.
Yes, in courses you are not allowed to make dives over 80% cns. Then you are learned about airbreaks. How you make them, 12-5-12, 25-6-25, or whatever (it depends on agency), is learned in courses. But doing airbreaks can be controversy too, back to backgas? Back to first decogas? Back to travelgas? When doing airbreaks and back to what gas? There is not 1 answer right. If you dont want to think about airbreaks, then take an 80%, normally you dont have problems with too much cns. But if you think I want to use oxygen, then you have to think about doing airbreaks or not and how. Not too difficult and I still prefer oxygen over 80%.
But you do not talk about depths of 100m, but shallower. You speak about 2 alu40 stages with 2 different decogases. You want to go back to 1 decogas.
First question: is that possible for your dives? Ali40 is not big. Ever calculated how much deco you can have as maximum out of 1 ali40? Or do you want to take the 2 ali40s with both same gas? Then there is absolutely no reason to go back to just 1 gas.
Then, why a 100% or 80% over an 50%? If I can do a dive with just 1 decogas, I would prefer to take a 50%.
But I think in your case with just 2 small stages I would stay with 50% and 100%. I dont see a reason to get to 80%. And if divecenters only fill 80% I dont see a problem to use that, but that is just when they dont want to fill 100%.
I use 50%-100% most times. Some prefer 40%-80%. Theoretically there is a chance that using 40% over 50% means you can stay 30-60 seconds longer on bottom and still have the 1/3 reserve. If you don't want to use only 'standardgases', then you can think about it. It is all about what plan you make.
Oxygen is theoretically the most clean gas, it is just decanted from a buffer to your cylinder. With 80% there is a possibility that the air from the compressor is contaminated (not clean enough for use with pure oxygen to hold cylinders in oxygenservice). Not as much you will get ill, but that you have to clean cylinders again.
I have used on 100+m dives 80% and 100% as last decogas, with both decogases I came up safe. My personal choice is 100%.