Neat sensors! Seems similar to other ones that have existed.
Looking at the command protocol it's basically 19200bps serial on a 3.3v serial bus. Doesn't seem ideal versus SPI or I2C. Could easily find a microcontroller that supports 2 or 3 uarts, the ability to read the DC battery voltage and talk CAN. Then you could convert these to run on a Shearwater controller that talks CANBUS. The protocol to talk to the sensors is well documented, the Shearwater CANBUS stuff isn't. I was starting to take a look at it. Downside is hard to mix say two Analog sensors and one digital without building the analog side again.
I think on my Prism2 the handset powers the board that reads the o2 cells for the handset, so that would bring power issues into play since higher power draw as previously stated.
Also from the datasheet:
"Do not use these products in safety critical devices or in any other application where
failure of the product could result in loss of life, personal injury, or damaged property.
This device and the sensors are not intended for aerospace, medical, breath monitoring,
diving, military or other safety-relevant applications.:"