I haven't tried the crushed neoprene, and I didn't even stay in a Holiday Inn Express last night, but here goes. When I bought my drysuit, I was looking at the same issues, after having, strangely enough, tried some suits at DUI Demo Days. I think everybody has pretty much nailed the differences between the suits: trilam is lighter in weight, dries faster, is less expensive, and may (depending on all kinds of things) be less restrictive; crushed neoprene is more durable, provides some insulating value (which can be a plus or a minus depending on your outlook), is more expensive, and dries slower. In addition, the crushed neoprene suits are usually less baggy, more streamlined. I thought the CLX 450 was a good compromise, more durable than the TLS 350, lighter and dries faster than the neoprene, and in-between on price (am I starting to sound like Goldilocks?). There is yet another option - the DUI FLX 50/50 - CF 200 crushed neoprene on the bottom and trilam on the top. I guess the expectation is that the lower part of the suit will get the most wear.