Hi All:
Sorry, I was on the road yesterday and didn't get a chance to respond to this LIVELY discussion.
Lamont, as I said from my earlier post:
Drewski:
Please explain to me the "mechanism" behind how Nitrogen Narcosis affects the brain and results in changes to perception, abilities and mentation. When you can do this, scientifically, then we'll have a conversation about "comparing" it to ETOH.
You responded with:
lamont:
It does appear though that at least some of the anesthetics like halothane and isoflurane affect GABA-A receptors which place them neuropharmacologically more similar to benzodiazepines and EtOH than your state of denial will accept.
Anyway, I'm claiming an analogy between diving under narocosis and driving under the influence as comparable human psychological issues involving equal amounts of denial and rationalization. The mechanism of action is largely irrelevant.
THEN you said:
lamont:
The more I think about it the more this is completely laughable, and a good example of why no matter how much diving Drewski has done his logic is flawed and not credible.
and:
lamont:
EtOH and Benzos affect primarily GABAergic receptors, Ketamine and PCP are NMDA receptor antagonists, LSD and DMT are 5-HT2A receptors antgonists , cannabis affects anandamide receptors, opiates affect opiate receptors, MDMA is a 5-HTergic reuptake blocker and releasing agent, etc.
and THEN, my favorite:
lamont:
They've all got widely differentiating mechanisms of action, and from where I'm sitting its up to you to prove that N2 is so substantially different from them, and that diving is such a different kind of activity that the analogy between driving under the influence of any of these chemicals cannot be applied to diving under N2.
Ok, let's take this stuff one item at a time.
First, WHY insult me like you did? I wasn't rude to you. I didn't say you were "wrong" or that "no matter how much diving you've done, YOUR logic is flawed" or that YOU were in "a state of denial" (your words about me, I might add). I just stated an opinion and then asked a question.
Second, although you gave some citations concerning anesthetics, how they bind to chemical receptors and - I love this term - how they "neuropharmacologically" affect the brain and body,
you still didn't answer the question DID YOU? Nothing of what you said explained how the increasing pressure of Nitrogen on the brain and nervous system affects a diver.
Third, after you
couldn't explain it - and let's just be clear here,
you couldn't explain it - you seemed somewhat frustrated. So, on your next post, you tried the old "bait and switch" routine. You said it was
"up to me" to prove that "N2 is so substantially different" from the other agents you discussed and "that the analogy between driving under the influence of any of these chemicals cannot be applied to diving under N2."
Well, when I went to school (and it's been a few years), the scientific method being taught first involved "observing" what you were interested in studying. Based on your observations, you then "hypothesized" a relationship. Then you set up an experiment and "tested" your hypothesis. If your tests indicated the hypothesized relationship was NOT likely random, you reported the results and discussed conclusions.
BUT, what YOU are suggesting is that the behavior of N2 and the other anesthetics has ALREADY proven to be similar (just because YOU said so) and it's up to ME to disprove it. Well, that's NOT the "scientific method," is it? To use a more current example, your "logic" goes something like this:
- Drewski says he's thinking about becoming Islamic.
- He hangs out with his Islamic friends.
- The third cousin of one of Drewski's Islamic friends is suspected of funding terrorism.
- Drewski needs to prove to us he's NOT a terrorist.
See what happens when you make ridiculous assumptions? One could conclude just about anything. That's why there is proven method of research to investigate stuff instead of just "saying it is."
BUT, I'm willing to take this discussion a step further. I'll answer the question you posed, the one I really don't have to answer. You asked me to prove "that the analogy between driving under the influence of any of these chemicals cannot be applied to diving under N2." OK, that's easy.
I go into a bar. Let's say I'm an occasional social drinker. Its been a rough day on ScubaBoard. I have 5 beers over one hour then leave. A few minutes later I swerve on the road and get pulled by a passing cop. I pass only a few of the sobriety tests the officer gives me and blow a .15 on the meter. I think everyone reading this would probably agree that Id be just as drunk regardless of if the bartender said dont worry about it, youll be fine you can handle it, or if I had attended a MADD meeting earlier in the evening warning about the tragedies and consequences of drunk driving. The point is, my attitude about drinking
wouldn't have affected the outcome.
Now, let's change the scenario. I'm a new diver. I don't read ScubaBoard (GASP!). My instructor tells me that Narcosis is a problem, but one that can be managed. He discusses the warning signs, how to "manage" narcosis during a deeper dive, what to be careful with. My friend, who's taking his dive lessons at another shop, does the "home reading" and glosses over narcosis. He reads ScubaBoard instead and gets LOTS of opinions. Hes told that "diving deep on air is BAD, AVOID it at ALL costs because you WILL get narc'd and you could DIE!" During his class, the instructor makes an offhand remark that "everyone diving deeper than 80 FT gets narc'd to some degree." He hears it and believes it.
A few months pass. My friend and I do several dives, between 30 and 60 FT. We decide to do a boat dive on a wreck, 110 FT deep. Neither of us is EAN trained, so we dive air. When we get to the bottom, my friend acts "weird." He starts laughing, doesn't respond to hand signals and is in obvious danger. He's narc'd. I get control of him, help him to the anchor line and we head to the surface. Back on the boat, he can't remember any particulars of the dive or what happened. I, on the other hand, remember everything including how I "rescued" him off the bottom, what depth we were at and our BT when the incident happened.
So what was the difference between my friend and I? For argument's sake let's say both of us are about of equal size and weight. We took similar classes and have identical experience. BUT, I was told that narcosis could be MANAGED. I
believed it. My friend, on the other hand, learned that he would probably get narc'd no matter what he did and, while in class, his instructor more or less confirmed this. So, he got narcd
because he believed he would.
This "effect" is called anticipated behavior modeling and was observed and tested with divers as test subjects back in 1965 by George Milner and Tom Mount (the same guy who's head of IANTD today). For a summary of the study, click
here. DAN also discusses this "issue" in terms of decreasing diver "anxiety." For that article, click
here. The key finding to take away from this study is that purely on the basis of knowledge, education and ATTITUDE, one can be better prepared for the effects of narcosis and
perform better in the actual environment. Diver experience, in this study, was NOT a factor that contributed to performance differences between the groups.
Want me to prove this MORE directly? Look at what you said in this thread:
lamont:
Everyone is narc'd to some degree below 80 fsw. The level of impairment is highly situationally dependent, and you can learn strategies to work around the impairment, but you're still impaired. The only way to remove the impairment is helium.
lamont:
I've had perceptual narrowing at 80 fsw on 30/30 trimix...
lamont:
Below 80 fsw is where I can feel my thoughts start to "loosen" due to the effects of narcosis. I'll typically start to daydream a little bit and need to concentrate a little bit more to stay focused.
lamont:
...now that you mention it, last time I was down at olive den and narc'd I had a "regulator not working" daydream. But I could look at my thought processes with some detachment and conclude I was just narc'd and there was nothing wrong with my regulator and those thoughts went away...
So, Lamont, there IS a BIG difference between N2, alcohol and the other anesthetic agents you mentioned.
No matter how much you know about beer and drinking, if you drink 5 beers you can still get drunk and still become impaired. But, its NOT the same for diving. All things equal between two divers, if one diver has been taught about the effects of narcosis, is prepared for it and has the right ATTITUDE, 5 ATM of pressure won't always impair this diver, even when the diver has minimal experience. BUT, conversely, if the another diver was told of the "negative effect" of narcosis and was also told that he or she "couldn't prevent it," the diver WOULD most likely be impaired. This effect, identified as anticipated behavior modeling, is NOT something that occurs when one consumes alcohol.
So, my response to your challenge is that, YES,
diving with N2 is substantially different than
driving with alcohol.
And, YES, given todays changes with gas and technology, Im ALREADY diving EAN below 80ft and wouldnt dream of diving air below 150 FT.
