Hmm.
Well, I really don't get overly worked up about pieces of gear, but I do a fair amount of diving and have done quite a few simulated OOA's and even a few real ones using an Air 2. Anyway, here are a few of my observations.
The air 2 isn't the most comfortable regulator in the world to breathe off of, but unless you plan on spending the bulk of your diving time bringing up OOA's, you will probably be able to suffer through the minute or so that you'll be using it for. That said, there are a good number of simple downstream octo's that breathe worse than the air 2 anyway.
I would recommend to anyone who uses an air 2 to pop it their mouth every once in a while for an ascent, just for the practice. It's even kinda fun.
One of the handiest things about an air 2 is the fact that it is very very easy to locate. This isn't usually a benefit I realize during an OOA rescue, but it has come in handy a few times when I've had to all of a sudden like enter the water without taking my eyes off of someone or something to locate my primary, or when I've been knocked in unexpectedly. A necklaced secondary offers this same benefit, only maybe better.
I use a G-250 as an alternate for any really deep diving that I do, not because I'm afraid that the air 2 will fail to deliver air, but because I think its clever to have adjustable regs down there so that you can deal with creeps (slow leaking through the reg) and extra big currents by just loading the spring a little. My every day recreational work rig is a 25/600 with an air 2 on a SP Classic (full on vest) BC. I prefer this set up mostly because it is very fast to get into if there's an emergency, but I like the way it swims too.
In summary, I have both set ups. They each have their place in diving. My advice would be for rec divers, the air 2 is great, it is convenient and certainly not unsafe. For those who will be doing deep, cave or decompression diving to get an adjustable second stage for that purpose.