I wrote earlier that once I switched to silicone seals, I have never trimmed a seal. I just searched my memory banks and realized I was wrong. I switched mostly to silicone 9 years ago, and I did trim the first one. I think the full story is instructive for this thread.
I switched to the Si-Tec ring system and silicone seals because back then drysuits, and particularly Whites suits, were having a tremendous problem with latex seals suddenly going bad, which I was eventually informed by chemists was almost certainly a job of poor manufacturing of the latex. When I got my suit back, I prepared to trim the neck seal the way I had always trimmed the latex seals, and if you are really curious, a search will reveal the thread in which I described the process. I cut a couple of rings and then wore the suit for a while to decide if it was loose enough, then cut another ring or two, etc.
Sometime later, I had to send the suit in for some other work, and the shop that had originally installed it (Dive Right in Scuba) sent me an email saying that it looked like I had trimmed the neck seal and wanted to know why. Had they sent the wrong size?
I have not trimmed any silicone seals since then.