Hello readers:
Helium and Oxygen
You would not gain much by breathing these gases. If you were to do this, eliminating the helium and breathing only oxygen would be better. Helium contributes to bubble growth just like nitrogen.
Even pure oxygen will not gain much for you as a diver. At pressure, you gain nitrogen quickly.
Astronauts
Hypobaric (altitude) exposure is a different matter. When going to altitude, you need to eliminate the nitrogen stored in your tissues; you are also breathing oxygen at altitude. With oxygen in the mask, you will have no inert gas uptake.
Astronauts prebreathe oxygen before EVA [extravehicular activity] because the pressure in the suit is 4.3 psi - equivalent to 30,000 feet.
The current prebreathe procedure at NASA is one I helped develop when I was at the Johnson Space Center.
Dr Deco :doctor: