fever blisters?

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Yes, herpes simplex is for life. Although recurrences can be quirky, for many individuals there are identifiable events that pretty consistently precipitate attacks.

As regards Blistex, I'm a little confused on the bad luck with the big v small tubes. Blistex makes a number of products for the lips--which are you using?

Best regards.

DocVikingo
 
I use the Blistex Medicated in the .21 oz... I can stick it in my laptop bag, or my pocket, or dive bag and its small enough it doesnt bust if something heavy is put against it accidentally. It also doesn't seem to leak if left in the car, while the larger tube leaked all over my cup holder...


<edited in note> I should point out that I don't like the blistex medicated for chapped lips. BLAH! The Blistex Herbal seems to work real well for that.
 
I wasn't sure if you meant bad luck in terms of convenience (which seems to be the case) or medical benefit.

Best regards.

DocVikingo
 
I get cold sores very occasionally, only at one corner of the mouth and generally mild - and yes I do consider myself lucky.

Like CBulla I can sometimes tell by the tingle that it's coming on - if I do, I get an ice cube, and hold that on to the area. Cheaper than blistex, and more likely to be in the house. It was something I read somewhere once, and it does seem to work to stop them appearing - or to relieve discomfort when they do. But like I said, I'm lucky to only get mild outbreaks.

On the other hand I seemed to get chickenpox twice - so I'm not gloating!
 
I don't have any science to back it up, but my experience is the same as clootie's. When you first feel an outbreak coming on with pain, burning, tingling, whatever and that first vesicle (bump) pops up, if you hold ice on the affected area until it begins to hurt, that particular outbreak won't progress further. Chances are, the blisters will just start to break out somewhere else a day or two later, but if you ice that area down, it will stop too. Overall I've found that you can lessen the extent of the blisters with this tactic if you catch it early enough.

Heat works too and you don't have to hold it on the outbreak as long as with ice. A brief application of hot water (hot enough to hurt, not hot enough to burn) soaked on the corner of a washcoth can sometimes arrest an outbreak. If you can't figure out what's hot enough to burn, then you're better off with the ice method.

Just my 2¢,

Bill
 
I've never tried the heat or ice tricks. My boss swears by a slice of lime saying that the acid in it curbs the outbreak.

One problem, many remedies..
 
Hi Trisha, and other suffers,

I get to see Herpes Simplex nearly weekly as a dentist.

It can also affect other parts of the mouth than just the lip. It will usually affect part of the nerve distribution on any part of the lip, hard palate and "attached" gingiva, ie., the gums. Canker sores affect the mucous membranes of the inside of the lip, cheeks, under the tougue.

It will usually affect KERATINIZED tissue rather than mucosa but can affect mucosa as well.

About 97% of the American population has antibodies to the virus...they have been exposed and infected. Not all these people will have fever blisters.

Herpes Simplex is rather contagious. I will reschedule a patient with an active sore and will not perform any dental surgery if a sore is present.

The virus has developed an infection strategy that is very effective....the affected part first tingles, itches, feels funny...the prodromal stage. Then you get vesicles filled with fluid that is FULL of virus particles. It is nearly impossible for the affected person to avoid touching the site. Then they may touch other parts of their body potentially transmitting it to that part as well...ie., the eyes. Surface may also become contaminated and if another person makes contact soon enough, they can become infected as well. Finally, a scab is formed that looks awful for about 3-5 days. Large lesions can scar or discolor in the sun.

The first infection is called Primary Herpetic Gingivostomatitis. It is miserable. Usually half the mouth is affected. There may be a low grade fever, malaise, sometimes cold like symptoms, severe pain of the gums, teeth, lips, etc. This lasts for about 10 days and goes away. Some infections may spread into the throat or affect the eyes.

You will want to avoid spicy, or salty foods and citrus or acid foods, cruncy foods. It is possible to get a secondary bacterial infection.

Following the primary infection, recurrent infections will occur...usually of the lips or gums. These recurrent infection usually affect the same place each time and as was mentioned by DocVikingo, can be triggered by a variety of causes.

Herpes can affect other parts of the of the body...dentists have to worry about Herpetic Whitlow of the fingers and cannot work when infected. Kissing, exchanging eating or drinking utensils can infect others.

As stated by others, Herpes Type I and Herpes Type II can cross infect and appear to be the same. Now how do you suppose that this happens???? Just don't do IT when infected..OK?!

Along with the previously stated treatments, a new medication called Abreva is available and for some, is effective.

Some people get good control of recurrent infections by taking L-lysine from the vitamin shelf at the pharmacy or grocery. It MUST be L-lysine not D-lysine. You take it like a vitamin, daily for prevention. Many patients go from an attack a month to 2 or 3 a year. For others, Lactobacillus milk or tablets can work.

The neatist treatment is something I use at the office...ready for this?...A RED LASER POINTER!

You got to the Office Depot or Best Buy and find the cheapest Red Laser Pointer. Try to find one that uses AAA batteries rather than the mercury silver batteries. These pointers are in the 640-680 nM wavelength and less than .5 mW. DO NOT SHINE IT INTO YOUR EVES or at a POLICE OFFICER! They can harm your eyes permanently, and the police will think you are using a laser site and HE MAY ARREST YOU OR DO BODILY HARM!!!!!

As soon as you feel a cold sore coming on, you expose the affected area for a total of 30 seconds for ANY PORTION OF THE LESION...A LARGE LESION WILL REQUIRE A MINUTE OR MORE OF EXPOSURE. Do it on once a day...more exposure is LESS effective...I don't know why.

This treatment is also about 70% effective for "canker" sores...so if you get ulcers from your regulator, the laser may help.

Now the "bad news"...this treatment is NOT FDA approved. Nobody in their right mind is going to do the testing necessary to create a medical device out of a laser pointer. There ARE, however, laser devices now in use for other ailments that use exactly the same wavelength that are approved.

My hygienist suffers from these sores and is forever "stealing" my pointers. If she "treats" the area during it's prodromal stage, it will go away without ever producing the vesicles or scab.

What is nice about this "trick" treatment is that you are simply using red light...the least energetic and non-ionizing to treat the sore. Most of the antiviral medications have side effects and can affect the liver. If used too often, the medication become less effective and resistant viruses are produces. The light has none of these drawbacks.

If any of you reading this try the laser, let me know how it works. It would be neat to collect some data on efficacy.

I'm not nuts! :rolleyes:

Good luck.

Laurence Stein, DDS
:doctor:
Disclaimer
(No representations are made that in any way offer a diagnosis, treatment or cure for any illness or condition, either discussed or implied. Answers to questions are offered as information only and should always be used in conjunction with advice from your personal diving physician/dentist. I take no responsibility for any conceivable consequence, which might be related to any visit to this site.)

For further reading on laser biostimulation, try:

http://www.laser-world.com/lllt/science.htm#4 This article is NOT specific to Herpes infection. However, it mentions wound healing and biostimulation by red laser. It is thought that the light increases the formation of collagen and stimulates the mitochondria to process energy better. The net result is more rapid healing.
 
Dr. Stein - on first reading your post about the red laser pointer for treatment of H. simplex, I thought you were nuts. As a cornea specialist, I'm referred patients with ocular herpes infections on a regular basis. I did a fair amount of research on H. simplex back during my cornea fellowship. I had never heard of this treatment, but my research days ended back in the mid-80s, before this technique was proposed. A Medline search does show some basis for the claim that low-level red laser treatment can benefit those with Herpes infections, though I would rate the support as a bit tenuous.

Most of the published data addresses pain relief in post-herpetic neuralgia from H. zoster, which is a different entity than a cold sore, which is an active H. simplex lesion. But a couple of studies looked at treatment of H. simplex.

This one showed improvement in 8/13 patients with recurrent H. simplex:

Fortschr Med. 1983 Jun 9;101(22):1039-41.

[Treatment of zoster, post-zoster pain and herpes simplex recidivans in loco with laser light]

[Article in German]

Landthaler M, Haina D, Waidelich W.

Red light of a krypton laser (lambda = 647 nm) was used for treatment of patients suffering from herpes zoster (n = 4), postherpetic neuralgias (n = 8) and herpes simplex recidivans in loco (n = 13). The afflicted skin was irradiated daily for ten days (laserpower 50 mw, exposure time 90 sec). Improvement was observed in 7 out of the 12 patients suffering from herpes zoster and postherpetic neuralgias respectively, and in 8 out of 13 patients afflicted with recurrent herpes simplex.


And this one actually showed a substantial increase in the recurrence-free interval between outbreaks after treatment with the laser, which might address Trisha's initial concern, which was with prevention:

J Invest Dermatol. 1999 Aug;113(2):221-3.

Low-intensity laser therapy is an effective treatment for recurrent herpes simplex infection. Results from a randomized double-blind placebo-controlled study.

Schindl A, Neumann R.

Department of Dermatology, University of Vienna Medical School, Austria. Andreas.Schindl@akh-wien.ac.at

Recurrent infection with herpes simplex virus is a common disease. Recently, alternative therapies have been introduced. Among those, low-intensity laser therapy mainly used for the acceleration of wound healing and in pain therapy has previously been shown to be of benefit in herpes zoster infections. In this study we evaluated the influence of low-intensity laser therapy (wavelength 690 nm, intensity: 80 mW per cm2, dose: 48 J per cm2) in 50 patients with recurrent perioral herpes simplex infection (at least once per month for more than 6 mo) in a randomized, double-blind placebo-controlled trial design. Patients in the laser group received daily irradiations for 2 wk, whereas patients in the placebo group were sham-irradiated. After completion of the laser/sham treatment, patients were asked to return to the Department of Dermatology, University of Vienna Medical School at the time of recurrence. All except two patients completed the study and were monitored for 52 wk. The median recurrence-free interval in the laser-treated group was 37.5 wk (range: 2-52 wk) and in the placebo group 3 wk (range: 1-20 wk). This difference was found to be statistically significant (p < 0.0001; Wilcoxon's Rank Sum Test). In conclusion, we demonstrated that a total of 10 irradiations with low-intensity laser therapy significantly lowers the incidence of local recurrence of herpes simplex infection. Since this athermic phototherapeutic modality represents a safe, noninvasive treatment, it might be considered as an alternative to established therapeutic regimens in this indication.


On the other hand, neither of these articles involved a large number of patients, and they employ repeated treatments with 50-80 mW lasers, which I believe is significantly higher than the power of the typical red laser pointer (the one in my desk says <5 mW). Further, at least one author remained unconvinced:

Oral Surg Oral Med Oral Pathol. 1988 Dec;66(6):654-8.

The soft laser: therapeutic tool or popular placebo?

Wilder-Smith P.

Department of Conservative and Preventive Denstistry, University of Heidelberg Dental School, West Germany.

Because of the alleged effectiveness of soft laser therapy in the treatment of a wide range of medical and dental conditions, it is becoming increasingly popular with both patients and practitioners. It was the purpose of this study to assess soft laser treatment of hypersensitive dentin, gingivitis, pulp-capped teeth, herpes labialis, and nausea. Clinical trails demonstrated no advantage in augmenting or replacing conventional treatment of these conditions with soft laser therapy, despite its positive effect on patient attitude toward treatment.


You would think that if this treatment were really quite effective, there would be more support in the literature. Is there more out there that I'm missing? The treatmenty seems harmless enough, though. I'm going to try it the next time I get a cold sore. And I'd encourage you or your colleagues to study this in a controlled fashion.
 
Sea Biscuit,

Thanks for the references and I hartily agree that more research is needed. I was intrigued by the idea like you now are and simply tried on patients as they came in...it seemed to work. I'd love to hear from you again if you have any success.

I wish a contolled study would be done. I picked up the technique from a dental "trade" magazine.

A "tech" savvy dentist suggested the treatment and I said, "What the heck"...the rest is history. In my hands it works. I don't charge my patients when I use it...er...what would the insurance code be for an Office Depot Special? :rolleyes:

I also find it useful following a procedure that has stretched the corners of the mouth and would otherwise become sore and chapped. Denture sore heal more rapidly following a denture adjustment. Irradiation of an incision line results in more rapid closure but total healing is the same. Irradiation of an extraction socket is supposed to reduce the incidence of "dry socket." These uses seem to involve the use of "biostimulation" to increase healing rates.

The few studies out there use more powerful lasers but for simple treamtments, .5mW seems sufficient.

There are a number of different lasers available in dentistry...this is the only "soft" type. All others either are capable of removing hard or soft tissues or changing the surfaces of hard tissues. The red laser does nothing like this.

I'm so glad I'm not really nuts :) though sometimes I go off the deep end.

Regards,

Larry Stein
 

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