Cthippo
Contributor
This will probably be TMI, but what else is new...I remember in my first aid class they said something to the effect of there are many conditions that can be improved with oxygen and only a few uncommon ones where it can be a problem so the default is everyone gets O2 if available. Maybe I'm mis-remembering, my card DID expire last year.
The big one you worry about oxygen administration harming the patient is if they have Chronic Obstructive Pulmonary Disease (COPD), which is mostly long term smokers. The chronic damage to the lungs over years has left them at a low level of function, and so instead of responding to high liveles of CO2 in the blood and breathing harder like most of us do, the run on what it called hypoxic drive. Basically, when their oxygen level gets too low they breathe. These are people who run 70-90% SPO2 on room air or low flow oxygen all the time. The problem is that if you put them on high flow oxygen (10 lpm or greater) they will no longer be hypoxic and stop breathing. OK, that sounds bad, but follow the thought through... If they stop breathing they will again become hypoxic and the drive will start up again. Theoretically they could go into an arrhythmia, but the takeaway is that the danger is probably overblown.
That said, there is newer research that seems to indicate that supersaturating (SPO2 >95%) patients with ischemic tissue injuries (heart attacks and strokes) leads to poor outcomes because of free radicals in the bloodstream. I admit I am not totally clear on the mechanism, but our county protocols are to titrate oxygen delivery for a target of 95% in healthy people and to tolerate desaturation as low as 89% in COPD patients if that is normal for them. As always, treat the patient, not the numbers.
The exceptions are DCS / barotrauma and burns / smoke inhalation. In the first case, high flow oxygen IS definitive treatment, or can be anyway, and in the second products of combustion (Carbon monoxide and cyanides) competitively bind to the hemoglobin receptors and we cannot tell which is which in the field.