Question Colonoscopy without Anesthesia?

[Akimbo]

I have to get a colonoscopy late this year and have read that a few people refuse anesthesia. This will my 4th colonoscopy. It would be nice not to have driving restrictions after the procedure since I live hours away and will be 75 years old. I recently read that some people have the procedure without anesthesia and it's not "that" uncomfortable. I have had a two bone marrow and two prostate biopsies without anesthesia and was fine with them so seem to be reasonably pain tolerant.

Comments and suggestions?

Ping: @rsingler and @Compressor

 

[kinoons]

It would be pretty hard to do placebo controlled randomized studies on colonoscopies. I suppose you could sedate all patients in both groups and not do the colonoscopy in the "placebo" group, but there may be some serious ethics problems getting the study approved. There is also the problem of people in the placebo group developing advanced cancer — sounds like a trial lawyer's wet dream.

Some people, like my wife, remember the whole procedure in detail so would have to be take off study.

You don’t need a placebo control - instead randomize to colo vs no Colo and see the results.

Additionally sham procedure randomized studies are absolutely performed for things like heart catheterization for stable chest pain and for knee surgery.

This (screening Colo vs presenting with symptoms) was recently done in Northern Europe. Much to the surprise of many it was an essentially negative study. The reduction in colon cancer related death was quite small (and arguably smaller than reported based on which method of interpretation is used) and the all cause mortality was dead even.

https://www.nejm.org/doi/full/10.1056/NEJMoa2208375

 

[Jim Lapenta]

My PCP is not pushing one for me. I turned 65 in Feb this year and had the Cologuard last year, and had it twice before with fecal occult in between. Cologuard is every 3 years for me. No history in the family of it and no issues on the non-invasive tests.
I was having some GI issues earlier this year and that was a possibility. But, I changed my diet and they went away. Turns out the issue was I have developed an intolerance for milk products. I had to switch to almon milk and take a lactaid or two if we have food with cheese.
I have known two people that had complications. My barber had to have surgery to fix his after being perforated and my therapists husband had the same thing happen to him.
I know from breaking my hip socket in 2022 that if I have to have one, knock me the f out!

 

[JuLe]

I did mine with no anesthesia, no sedation, no cath.

Not that bad really. Uncomfortable occasionally going around bends but tolerable.

Drove myself there and back.

All told, the prep was worse.

Same with me. Can't say I enjoyed it, but been thru (much) worse pain when being patched up for various things over the years.
The prep was definately the worst part of it.