Lightning Fish:
When I take pseudoephedrine orally, it clears me up but later I am really congested. Is it rebound or is the congestion just accentuated because I spent the last several hours clear and able to breath?
Yeah thats why, unlike Scubadoc, I hedge and say that
generally pseudoephedrine causes
less rebound in
most people. Im sure that in a lot of people it probably causes no rebound at all, but in some like you it might cause rebound congestion. In someone else, it could cause other side effects. Most rules have exceptions, but IMHO if the exception is uncommon and not significant for most people it is not a reason to write a new rule. If pseudoephedrine causes significant rebound in
you that is a perfectly valid reason for
you to not use pseudoephedrine. But IMHO, it is not sufficient reason to tell others that pseudoephedrine will definitely cause significant rebound in
them. Mention the
possibility, sure, but mention it
as a
possibility.
Lightning Fish:
A drug is a drug is a drug ... How is the method of ingestion important in this case?
Yeah a drug is indeed a drug, but an apple is an apple and an orange is an orange. Just because theyre both fruits doesnt mean that
everything about one automatically applies to the other. In your post you talked about rebound congestion from pseudoephedrine and used your wifes friends experience with nasal spray as an example to back up your claim. The problem with your example is that pseudoephedrine isnt taken as a nasal spray (with
rare exceptions)- it is a pill. Decongestant nasal sprays that are sold to the general public are
different drugs (like oxymetazoline, xylometazoline, phenylephrine, etc.) The rebound congestion from using decongestant nasal sprays is well documented and easily observable after using the spray for just a few days. The same apparently cannot be said of pseudoephedrine for most people.
Lightning Fish:
Bill, what is your expertise?
I am a physician specializing in diving and hyperbaric medicine and subspecializing in ENT and allergy/immunology. I am also a research scientist doing laboratory and clinical research on the effects of sympathomimetic amines (like pseudoephedrine) on the mucosa of the oropharynx and upper airways. I currently have a controlled double-blind study of over 2500 normal volunteers about to be published in a major peer-reviewed journal that shows that pseudoephedrine has no rebound effects. Actually, BillP is just my board name. I picked it because the initials are the same as mine. I am really Brad Pitt. I would like for you to be my guest to see my new movie Mr. And Mrs. Smith. Then maybe Angelina and I can have you over to our place afterwards for dinner and whatever
OK, Im just kidding. I claim
no special expertise on this board. IMHO, people are
way too ready to believe anything they read on the Internet, and its
way to easy to make things up as you go along. Thats why I referred you to a quote from Scubadoc/Ern Campbell that you could read for yourself. Dr. Campbell is a known quantity. He has his scuba-doc.com diving medicine website, and has published articles in scuba diving magazines and in DANs own Alert Diver magazine. IMHO, having me (or anyone else for that matter) simply say because I say so, someone told me, I read once somewhere isnt good enough in some cases- like when dispensing medical advice. It's too easy for people to post what they have misunderstood about what they saw, heard, or read- or frankly just to make it up. The information I post sometimes stands on its own and you can take it or leave it FWIW if you want, but I
think its good information, and I try to get you verifiable sources to back up my claims when I can. And I ask other people to do the same when they can.
Just my 2¢,
Bill