Tissue stress associated with bubble formation; potential benefits of diving enriched air

[KenGordon]

Could you describe those circumstances? In a recreational context how is that happening? You're on 36% and drop to 220fsw? Pulmonary O2 toxicity is minor compared to your other issues if that happens. In a non recreational setting even hard to see. You run out of back gas and switch to 100% at 60fsw, risking drowning from CNS toxicity vs. drowning being out of breathing gas? Possible, but again pulmonary damage is not your primary concern.

Five something hours in a chamber, starting with some time at 18m on 100% O2 with 5 minute air breaks every half hour or so. Then a load at 9m etc. And then if you were not bent (or fixed) but still have symptoms you might get a few more hours on the following days to see if that helps. None of that makes anyone's lungs and throat feel good.

You don't need to be doing anything special to end up in a chamber.

 

[uncfnp]

(Venous gas embolism as a predictive tool . . . ) paper cited by Storker) that bubbles can, and probably do, damage the intravascular endothelium to a certain extent.

Hmmm. Acute MI is also associated with endothelium damage and inflammation. Long shot here but makes me wonder if "silent bubbles" might be an additional risk factor in 50 something divers. Seems like this group has a disproportionally high incidence of cardiac events. Of course those bubbles would need to be on the arterial side.

 

[dmaziuk]

Hmmm. Acute MI is also associated with endothelium damage and inflammation. Long shot here but makes me wonder if "silent bubbles" might be an additional risk factor in 50 something divers.

88% chocoloves are 2 for $5 today at the local whole paycheck
Protective effects of dark chocolate on endothelial function and diabetes. - PubMed - NCBI
Acute dark chocolate and cocoa ingestion and endothelial function: a randomized controlled crossover trial. - PubMed - NCBI
... there's more ...

 

[Storker]

Could you describe those circumstances? In a recreational context how is that happening?

Table 6.

EDIT: Or what @KenGordon said.

 

[uncfnp]

88% chocoloves are 2 for $5 today at the local whole paycheck
Protective effects of dark chocolate on endothelial function and diabetes. - PubMed - NCBI
Acute dark chocolate and cocoa ingestion and endothelial function: a randomized controlled crossover trial. - PubMed - NCBI
... there's more ...

Now that's the kind of preventive medicine I like. I wonder if the dark chocolate espresso beans I've been snacking on count?

 

[Storker]

Now that's the kind of preventive medicine I like.

OTOH, you'd probably prefer to stay off the Viagra: Chocolate Good, Viagra Bad

 

[dmaziuk]

... but only if you have a dive lasting longer than 4 hours.

 

[Storker]

Dang, was it the dive that had to last more than four hours?

 

[dmaziuk]

it was 45 minutes in rat time

 

[uncfnp]

A glass of red wine can limit endothelial dysfunction and oxidative damge! Win, win!

Red wine polyphenols prevent endothelial dysfunction induced by endothelin-1 in rat aorta: role of NADPH oxidase. - PubMed - NCBI