no, hdugan is correct. You cannot change from air mode to Nitrox mode once you've started diving. You may not be able to change mode at all, I don't recall - but usually people don't care so much about changing from Nitrox to Air mode since you can just change the O2 percentage.
Strangely there is a difference between the Gekko and the Vyper
From the Gekko Manual
NOTE!
You can change from Air mode to Nitrox mode at any time. It is however not
possible to revert back to Air mode from Nitrox mode before the instrument has
counted down the no-flying time.
When planning both air and nitrox dives during the same dive series, you should
set the instrument in Nitrox mode and modify the gas mix accordingly.
From the Vyper manual:
NOTE!
IT IS NOT POSSIBLE TO CHANGE BETWEEN THE AIR, NITROX AND
GAUGE MODES BEFORE THE INSTRUMENT HAS COUNTED DOWN
THE NO-FLYING TIME.
IF YOU DIVE WITH THE GAUGE MODE, IT IS NOT POSSIBLE TO
CHANGE BETWEEN THE MODES WITHIN 48 HOURS.
WHEN PLANNING SUBSEQUENT AIR AND NITROX DIVES DURING
THE SAME DIVE SERIES, YOU SHOULD HAVE THE DIVE COMPUTER
SET IN THE NITROX MODE AND MODIFY THE GAS MIX
ACCORDINGLY.