I have heard such stories, but it is hard for me to figure out how one tank can be filled with helium and the other with something else. I have done a ton of partial blending in my life, and I can't figure out what kind of a sequence would be required for me to make such a mistake. I have certainly made mistakes that were caught when we checked the blend, but I am having trouble figuring out how I could make that one.
Start with empty tanks. Close isolator. Add oxygen to right tank. Get distracted by something and come back later. Add helium to left tank. Top off left tank with air to maximum pressure. Analyze left tank and notice that the mix is wrong, then "fix" it by venting some gas and then boosting or whatever. Now you have a full left tank that analyzes correctly, and a right tank containing only oxygen.
Start with empty tanks. Add helium. Add oxygen. Close isolator. Top off left tank with air to maximum pressure. Now you have a full left tank that analyzes correctly, and a right tank containing hyperoxic heliox.
Probably some other ways as well.