Don't let your guard down too much around the old folks, though; nearly everyone who gets infected has at least a brief window of being pre-symptomatic but still contagious.
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This also means that those who were vaccinated can also spread the virus around.New news and it's bad. Earlier on in the pandemic, the info. I saw painted a picture where people who'd had COVID-19 before were at extremely low (but not 'no') risk for reinfection later. Then this morning from MDLinx I got an e-mailing with a link to an article:
New study finds reinfection by SARS-CoV-2 in healthy young adults is common
I don't know whether you guys can see the article open when you click the link or not. I'll copy & paste some snippets:
"Paper title:SARS-CoV-2 seropositivity and subsequent infection risk in healthy young adults: a prospective cohort study"
"Bottom Line: Although antibodies induced by infection to SARS-CoV-2 are largely protective, they do not guarantee effective immunity against subsequent infection, as evidenced through a longitudinal, prospective study of young Marine recruits. Previously infected study participants identified by seropositivity are susceptible to repeat infection, with nearly one-fifth the incidence rate of those without evidence of previous infection. Among the seropositive group, those who became infected again had lower antibody titers than those that were uninfected, and most lacked detectable baseline neutralizing antibodies. Findings suggest that COVID-19 vaccination may be necessary for control of the pandemic in previously infected young adults."
"Results: Among 189 seropositive participants, 19 (10.1%) had at least one positive PCR test for SARS-CoV-2 during the six-week follow-up. In contrast, 1,079 (48.0%) of the 2,246 seronegative participants tested positive. The incidence rate ratio was 0.18 (95% CI 0.11-0.28, p<0.00001). Among seropositive recruits, infection was associated with lower baseline full-length protein IgG titers (p=<0.0001). Compared with seronegative recruits, seropositive recruits had about 10-fold lower viral loads and trended towards shorter duration of PCR positivity (p=0.18) and more asymptomatic infections (p=0.13). Among seropositive participants, baseline neutralizing titers were detected in 45 of 54 (83.3%) uninfected and in 6of 19 (31.6%) infected participants during the 6 weeks of observation."
"Study Conclusions: Seropositive young adults had about one-fifth the risk of subsequent infection compared with seronegative individuals. Although antibodies inducted by initial infection are largely protective, they do not guarantee effective SARS-CoV-2 neutralization activity or immunity against subsequent infection. These findings may be relevant for optimization of mass vaccination strategies."
This is interesting for a range of reasons. The good news is, prior infection appears protective...but not fully protective. The bad news...is our hopes for 'vaccine passports' or showing a medical letter documenting prior infection with resolution may not be the badge of coronavirus purity we might wish. These were young Marine recruits, probably a healthier group than the general American population.
Richard.
Thank you Richard for the excerpt above.
I flew into Puerto Rico in a United flight, and even do everyone is wearing a mask, the middle seat is occupied. There is no social distance in the plane. The risk is there!.
Yes, not new information. The vaccination is for you, not for others. You continue to wear a mask and socially distance, for others.This also means that those who were vaccinated can also spread the virus around.
Several of us can't get the vaccine and need herd immunity. This shows that is not possible.
Thanks for posting. After first read a couple of thoughts.New news and it's bad. Earlier on in the pandemic, the info. I saw painted a picture where people who'd had COVID-19 before were at extremely low (but not 'no') risk for reinfection later. Then this morning from MDLinx I got an e-mailing with a link to an article:
New study finds reinfection by SARS-CoV-2 in healthy young adults is common
I don't know whether you guys can see the article open when you click the link or not. I'll copy & paste some snippets:
"Paper title:SARS-CoV-2 seropositivity and subsequent infection risk in healthy young adults: a prospective cohort study"
"Bottom Line: Although antibodies induced by infection to SARS-CoV-2 are largely protective, they do not guarantee effective immunity against subsequent infection, as evidenced through a longitudinal, prospective study of young Marine recruits. Previously infected study participants identified by seropositivity are susceptible to repeat infection, with nearly one-fifth the incidence rate of those without evidence of previous infection. Among the seropositive group, those who became infected again had lower antibody titers than those that were uninfected, and most lacked detectable baseline neutralizing antibodies. Findings suggest that COVID-19 vaccination may be necessary for control of the pandemic in previously infected young adults."
"Results: Among 189 seropositive participants, 19 (10.1%) had at least one positive PCR test for SARS-CoV-2 during the six-week follow-up. In contrast, 1,079 (48.0%) of the 2,246 seronegative participants tested positive. The incidence rate ratio was 0.18 (95% CI 0.11-0.28, p<0.00001). Among seropositive recruits, infection was associated with lower baseline full-length protein IgG titers (p=<0.0001). Compared with seronegative recruits, seropositive recruits had about 10-fold lower viral loads and trended towards shorter duration of PCR positivity (p=0.18) and more asymptomatic infections (p=0.13). Among seropositive participants, baseline neutralizing titers were detected in 45 of 54 (83.3%) uninfected and in 6of 19 (31.6%) infected participants during the 6 weeks of observation."
"Study Conclusions: Seropositive young adults had about one-fifth the risk of subsequent infection compared with seronegative individuals. Although antibodies inducted by initial infection are largely protective, they do not guarantee effective SARS-CoV-2 neutralization activity or immunity against subsequent infection. These findings may be relevant for optimization of mass vaccination strategies."
This is interesting for a range of reasons. The good news is, prior infection appears protective...but not fully protective. The bad news...is our hopes for 'vaccine passports' or showing a medical letter documenting prior infection with resolution may not be the badge of coronavirus purity we might wish. These were young Marine recruits, probably a healthier group than the general American population.
Richard.
The question becomes why can't they, and what can be done to develop vaccines they can g