Depends on face shape, mask shape, phase of the moon and other seemingly random events.
Some dives i wont have a drop in my mask, other times it'll need clearing every few minutes despite removing/refitting. Face shape changes with a hood in and a regulator in as well.
The people i know with moustaches use vaseline without damage to their masks and say it helps then.
The most irritating leak i find is a tiny one that leaves a constant high pitched buzzing noise as air leaves the mask.
If the mask is leaking badly, try on different masks to see if one is a better fit. Other than that, just fiddle until you're happy with the amount it leaks and prepared to clear every once in a while.
I occasionally keep a small bit of water in the mask - if the lense mists up i can just shake my head to clear the lense.
My face is "odd" - ive only ever found one mask that fits properly and thats Mares Opera. All others ive tried leak around the top corners.