Just returned from a long weekend stay and diving with OF. This was our third stay at OF and 7 trip overall. Just some observations.
1. Car rental. I think Avis is better than Andys and Avis is owned by a family that has been in the business since at least the late 70s. Andys is good but I know people who have had issues with Andys. I have never had an issue with Avis. Every time I have booked with Avis, my time getting the car and dropping off has been a matter of minutes. They are fast and efficient.
2. Diving. If diving on the East end OF is tops. Take advantage of the service offered of leaving your gear at the end of the day. They will wash, dry and have it on the boat for you for each day of diving. Reserve in advance. Try the lionfish tacos at Eagle Rays after your dives.
3. Driving. Driving on the East end is easy. We drove most of the time on the east end with hardly seeing another car. 7mb and leaving the airport another story. For the drive from the airport to the East End, just familiarize yourself with maps, remember to stay on the left and you should be fine. As mentioned for two lane roads into round abouts its easier and best to stay in the left lane.
4. Cruise ship crowds. Check cruise.tt to see the schedule of ships arriving Georgetown the week you are there. I avoid GT like the plague anytime ships are docked. They may be bused to Rum Point so plan accordingly.
5. I think if I were to plan a week on GC with a nondiving spouse, I would plan part of the week on the East End to take in the peace and quiet and old cayman vibe but would also enjoy part of the time staying right on 7mb to hang out, walk the beach and enjoy what the west side of the island has to offer.
Enjoy your vacation!