Impossible to say with the given info but from the post it sounds like the reaction is limited to the site of trauma/punctures. If the reaction is occurring away from the wounds, anywhere there were not punctures, it may be more concerning.Wow, no vinegar? I'm surprised because I'd believed that would help dissolve the calcium of the spines.
But Doctor Vikingo was our guy for many years! So that's the word.
My concern was that the rash is spreading, as per OP. Isn't that indicative of this going in the wrong direction?
But 4 days into the response I would be very surprised by an acute anaphylactic type reaction. Also reassuring is the fact she reports no toxic symptoms such as nausea/vomiting, lightheadedness or otherwise in distress.
Edit, reread post and seems even longer than 4 days. Seems it is possible to develop a contact dermatitis (delayed hypersensitive reaction) similar to poison oak.
Of course all this is just general info and may not apply to the op.