True, but what about one of your two regulators blowing an HP DIN O-ring near the
end of your planned bottom time? That is first thing that goes wrong, Now let's say you are in the North Atlantic, miles offshore. The current is high, visibility is 15' and no other divers are in sight when you look up from your valve shut-down... not planned but but it happens. That is the second thing that went wrong. After studying accidents over the years it is not unusual to see a cascade of three or more problems that contributes to a diver's death. What else would you like to add? During a wreck penetration perhaps? How important is that 10 seconds of lost gas from both cylinders now?
On the other hand, what is so onerous about reaching back and cycling the isolation valve? It takes about a second to crack it open on valve-down doubles.