Given this is a "new diver forum" about body position, not the technicalities of Intermediate pressure discrepancies...
Yes, many basic model regulators don't breathe so well when you're upside down; nothing a good cough or a small push on the purge button can't rectify.
In recreational diving; assuming you are correctly weighted, there are no body positions that are detrimental to your general well-being beyond those that might cause you some personal discomfort based on your own body shape and size, and any physiological problems you may have (bad back, gammy knee, whatever)
On the other hand, body positions to be avoided because they make you look a bit daft include permanently swimming head up and feet down, or feet up and head down, because this generally means you are either incorrectly weighted or not operating your gear correctly. Also you end up bashing into the coral, which is never a good thing, either for you, or it. Standard dive position is, of course, horizontal, streamlined and looking like a megastar, but if you want to float on your back, upside down, at an angle, do barrel rolls, do forward rolls, and as Doc Harry said, enjoy the 3D experience, then go for it! It's fun! It's one of the reasons I love to dive!
(As long as you do it safely!)
Cheers
C.