The cylinder neck o-ring? I guess that is technically true.
Has someone seen a cylinder o-ring fail with loss of gas? Honest question. Had that cylinder been inspected and received a fresh o-ring within the past couple of years? Some trimix bailout cylinders are "permanent" and never serviced for up to decades. So yeah your comment does matter here.
The H valves I think have two o-rings at the joint? Just like manifolds? I mean it literally is exactly like a manifold, and serves the similar purpose of protecting against gas loss due to regulator failure. Plus regulator redundancy.