You may have had a chance to review these articles, but perhaps not. They provide some background:
http://www.abysmal.com/web/library/articles/the_elusive_bubble.html
http://www.abysmal.com/web/library/articles/abys1.pdf
http://www.abysmal.com/web/library/theory.html
The 'rate of ascent to benefit' ratio (ascent rate allowing most efficient gas transfer/tissue offgassing) ascribes a curve, so eventually you'll reach a point of diminishing returns, however,
in general a slower ascent rate
during offgassing is often preferable.
Before you hit the point in your ascent where you are 'off-gassing', however, you are still 'on-gassing', or put another way you are continuing to experience tissue loading in those tissue groups that absorb gas more rapidly.
Therefore during that portion of your ascent while you are still 'ongassing' or continuing to incur decompression obligation, you may choose to ascend at a more rapid rate. The rationale is that for every minute you remain below that point where you begin offgassing you will continue to incur additional decompression obligation.
So the simple answer is that your initial ascent rate to that point where you begin offgassing can be more rapid, and your rate of ascent thereafter should be significantly slower.
But it isn't a simple process. Different tissue groups ongas and offgas at varying rates, therefore during your ascent from depth (depending on how long you remained at what depth) some tissue groups will be ongassing while others are offgassing. Identifying 'the point where you begin off-gassing' may depend on which tissue group is controlling your ascent - offgassing fastest.
Other divers will have their own approaches, but my buddy and I ascend at a rate somewhat faster than 30fpm to our deep stop, 30fpm from deep stop to 70' stop, and more slowly from 70' during the deco curve thereafter. But we dive trimix. The 'most efficient' ascent rate from 70' on can possibly be best described by thinking of your rate of ascent in terms of ever more frequent pauses (e.g. if every 10 feet, if every 5 feet - theoretically if the diver could hold a momentary pause every 1 foot - the deco curve would really smooth out). Most divers I know pause every 10 feet or so to slow their ascent rates until they hold their stops.
BTW - While you'll likely hear more in posts to follow, I'll point out that the foundation of your post - 'diving to sufficiently deep depths for long enough that you need decompression profiles' - ON AIR - is unwise.
A case might be made that you have more to be concerned about from the effects of nitrogen narcosis impacting your decision-making over time at depth than you do from the theoretical long-term effects of microbubbles.
FWIW,
Doc