Hello readers:
Exercise and NASA
In the NASA studies, I examined the effect of exercise during the decompression phase and during the pre-decompression phase. Within a couple of hours prior to depressurization, exercise was found to be a deleterious quantity as concerns DCS. [Ref 5]. This we attributed to micronuclei generation, but there is not any proof that this is the mechanism.
Light Exercise During Decompression
If it is not too strenuous, exercise during decompression will increase tissue blood flow and promote nitrogen washout. [Ref. 10]. This is beneficial to divers.
Exercise and Bubble Formation
While exercise as a negative effect when decompressing to altitude [equivalent to a saturation-excursion dive], it does not appear to be the case when diving. This is probably because bottom pressure will eliminate any large bubble nuclei generated by the prior exercise. Considerable work has been performed concerning altitude depressurization because of its association with astronauts and extravehicular activity. In particular are the relationships of activity levels during the low-pressure [decompression] phase of the activity.
In 1989, I hypothesized that the reason decompression sickness was observed in ground-based tests of astronaut decompression procedures and not in null gravity was the reduction in number of tissue micronuclei in space because of the reduced musculoskeletal activity. Prior to this hypothesis, only exercise effects while on the bottom were considered.
Exercise Prior to Decompression
The NASA work generated considerable interest in the hyperbaric research community. By serendipity, work has been focus in depressurization and exercise separated by many hours. Curiously, it has been found that this type of predive exercise is a mitigating factor for DCS. [Ref. 2, 3, 8, 9, 11, 14].
Nitric oxide has been implicated as playing a role [Ref. 12, 13]. A recent study also indicates that hyperbaric oxygen several hours before a dive is beneficial. [Ref. 4].
Dr Deco :doctor:
References :book3:
1. Berge VJ, Jorgensen A, Loset A, Wisloff U, Brubakk AO. Exercise ending 30 min pre-dive has no effect on bubble formation in the rat. Aviat Space Environ Med. 2005 Apr;76(4):326-8.
2: Blatteau J, Boussuges A, Gempp E, Pontier JM, Castagna O, Galland FM, Robinet C, Bourdon L. Hemodynamic changes induced by sub-maximal exercise prior to a dive and its consequences on bubble formation.
Br J Sports Med. 2006 Nov 30;
3: Blatteau JE, Gempp E, Galland FM, Pontier JM, Sainty JM, Robinet C. Aerobic exercise 2 hours before a dive to 30 msw decreases bubble formation after decompression. Aviat Space Environ Med. 2005 Jul;76(7):666-9.
4. Butler BD, Little T, Cogan V, Powell MR. Hyperbaric oxygen pre-breathe modifies the outcome of decompression sickness.Undersea Hyperb Med. 2006 Nov-Dec;33(6):407-17
5: Dervay JP, Powell MR, Butler B, Fife CE. The effect of exercise and rest duration on the generation of venous gas bubbles at altitude. Aviat Space Environ Med. 2002 Jan;73(1):22-7.
6: Dujic Z, Palada I, Valic Z, Duplancic D, Obad A, Wisloff U, Brubakk AO. Exogenous nitric oxide and bubble formation in divers.Med Sci Sports Exerc. 2006 Aug;38(8):1432-5.
7: Dujic Z, Obad A, Palada I, Ivancev V, Valic Z. Venous bubble count declines during strenuous exercise after an open sea dive to 30 m.Aviat Space Environ Med. 2006 Jun;77(6):592-6.
8: Dujic Z, Palada I, Obad A, Duplancic D, Bakovic D, Valic Z. Exercise during a 3-min decompression stop reduces postdive venous gas bubbles. Med Sci Sports Exerc. 2005 Aug;37(8):1319-23.
9. Dujic Z, Duplancic D, Marinovic-Terzic I, Bakovic D, Ivancev V, Valic Z, Eterovic D, Petri NM, Wisloff U, Brubakk AO. Aerobic exercise before diving reduces venous gas bubble formation in humans. J Physiol. 2004 Mar 16;555(Pt 3):637-42. Epub 2004 Jan 30.
10. Jankowski LW, Tikuisis P, Nishi RY. Exercise effects during diving and decompression on postdive venous gas emboli. Aviat Space Environ Med. 2004 Jun;75(6):489-95.
11. Loset A Jr, Mollerlokken A, Berge V, Wisloff U, Brubakk AO. Post-dive bubble formation in rats: effects of exercise 24 h ahead repeated 30 min before the dive. Aviat Space Environ Med. 2006 Sep;77(9):905-8.
12. Wisloff U, Richardson RS, Brubakk AO. Exercise and nitric oxide prevent bubble formation: a novel approach to the prevention of decompression sickness? J Physiol. 2004 Mar 16;555(Pt 3):825-9. Epub 2004 Jan 14.
13. Wisloff U, Richardson RS, Brubakk AO. NOS inhibition increases bubble formation and reduces survival in sedentary but not exercised rats. J Physiol. 2003 Jan 15;546(Pt 2):577-82.
14. Wisloff U, Brubakk AO. Aerobic endurance training reduces bubble formation and increases survival in rats exposed to hyperbaric pressure.
J Physiol. 2001 Dec 1;537(Pt 2):607-11.
The next class in Decompression Physiology for 2007 is August 18-19. :1book:
This class is at the USC campus in Los Angeles.
http://wrigley.usc.edu/hyperbaric/advdeco.htm