How can the science be dead on, but not relevant to this scenario? Think about it. You add more weight to your ankles then you are used to having. This means that when you move your legs you have to exert more energy to move your legs. The more energy you exert the more oxygen your muscles need. The more oxygen your muscles need the more you breath. The more you breath the faster you suck down a tank of air.
So again, how can the science be dead on, but not relevant to this scenario?
Look at what OE2X said "I personally don't like using the weights. At the end of a dive where I have used them my legs are much more fatigued than the same dive without."
His legs would be more fatigued because he worked his legs harder. That would affect the SAC rate. It will affect everybody differently depending on how good of shape you are in, how good of a SAC rate you have to begin with, how much weight you wear on your ankles, the environmental conditions, etc, but it does affect the SAC rate. You can't say "It will not make one bit of measureable difference." in on post and turn around the next and say the science is dead on in the next. That's like saying a wheel is round, but it doesn't roll.