Absolutely yes.Is there a significant difference between diving 45 feet at 7000 feet vs diving 45 feet at sea level and then taking and elevator up to 7000 feet in a matter of minutes.
If you surfaced with a supersaturation of 85% at sea level (quite acceptable) it would increase to 126% during the elevator ride -- bad news. If you dove for the same bottom time at 7000 ft, your supersaturation upon surfacing would be 94% (on par with the DSAT algorithm that backs the PADI recreational dive planner) -- so pretty safe.
(This is ignoring the bubble expansion present in the elevator case. That makes that case even worse.)