I added the altitude capability to my spreadsheet. You can enter the final destination altitude and the time it takes to get there and it will happily calculate all the tissue compartment pressures, CurGF, SurGF, and more. It adds an altitude segment after the surface interval (air and O2 if selected). From what I remember the changes in GF and TCP's were modest after arrival at altitude.
I don't understand what the big issue is. At 7,000 ft altitude the surface pressure is 0.77 atm. All the tissues "see" is a drop in inspired inert gas pressure and therefore off gassing until the TCP's reach saturation. The tissues don't understand altitude just pressure differences. Interestingly, on a flight at cruising altitude I turned my Perdix on and it showed the decrease in cabin pressure. I remember seeing about 860 mbar. The tissue compartment display actually showed some compartments pressure above the ambient pressure line and therefore off gassing. Since the computer was not in dive mode the NDL and dive time stayed at 0.
I understand the dangers of commercial flying. Typically, the cabin pressure is roughly at the same pressure as being at an altitude of 8,000 ft. The ascent to cruising altitude is quick (~20 minutes) placing greater stress on the tissues as opposed to driving there. Also, if a window blows out the sudden decrease in cabin pressure could be devastating to someone with elevated TP's above surface pressure.