The underlying principle is that in GUE we are thinking divers. The reasons for the gasses choose are:
1. Acceptable PPO2 (Unbendable rule: 1.2 max working, 1.4 contingency max working, 1.6 max resting deco)
2. Acceptable narcotic depth - remember this is a combination of PPN2 and gas density causing CO2 rentention - (Unbendable rule: END shallower than 100')
3. Familiarity and personal history with minimum deco limits and/or decompression schedules on each of the standard gases
What you choose to breathe must take the above factors into account.
In addition, it is hard to get Nitrox in the Boston area, so I completely understand that problem. Another is logistics of what's in your tanks. As a Tech 1 diver, I tend to have 21/35 in one set, 30/30 in another, and 32 in a third set of doubles. I typically shore dive on a leftover fill of 32. I generally won't fill a set with air, cause knowing my luck, I'll get blown out of that shallow/shore dive, then have to dump and refill for a wreck dive. Air may be an acceptable option in the pool or shallow bug dives (30'), but around 50' the minimum deco limits for air and nitrox32 diverge. So I generally just find it easier to dive nitrox all the time.
Why not best mix:
We don't choose different flavors of nitrox (28, 36 etc). As a Tech 1 diver, I have a lot of personal experience on 32, 30/30 and 21/35. I know what the deco looks like and I know how myself and my regular buddies react on those schedules. If there were many other gas options, our experience would be diluted over many more deco schedules.
Bottom line is, however, that compromising sucks. If all of us actively diving in Boston DEMANDED nitrox, the availability would go up and the price down.