DevonDiver
N/A
O2 Tox Symptoms (CNS Toxicity/Paul Bert Effect)
CON - convulsions, short tense muscle contractions (tonic); followed by rapid spasms/convulsive jerking (clonic)
V - visual disturbances, especially tunnel vision or blurred vision
E - ear ringing, such as tinnitus
N - nausea, vertigo and dysphoria ("just didn't feel right")
T - tingling, muscle twitching and cramping
I - irritability, personality changes and anxiety
D- dizziness, confusion and decreased consiousness
Illustration of symptom onset, from study:
Oxygen Poisoning at 90 ft (27 m) in the Dry in 36 Subjects in Order of Performance
by K W Donald (1947). px"Oxygen Poisoning in Man: Part I". British Medical Journal
[TABLE="width: 500"]
[TR]
[TD]Exposure (mins.)[/TD]
[TD]Num. of Subjects[/TD]
[TD]Symptoms[/TD]
[/TR]
[TR]
[TD]96[/TD]
[TD] 1[/TD]
[TD]Prolonged dazzle; severe spasmodic vomiting[/TD]
[/TR]
[TR]
[TD]6069[/TD]
[TD]3[/TD]
[TD]Severe lip-twitching; Euphoria; Nausea and vertigo; arm twitch[/TD]
[/TR]
[TR]
[TD]50554[/TD]
[TD]4[/TD]
[TD]Severe lip-twitching; Dazzle; Blubbering of lips; fell asleep; Dazed[/TD]
[/TR]
[TR]
[TD]31354[/TD]
[TD]4[/TD]
[TD]Nausea, vertigo, lip-twitching; Convulsed[/TD]
[/TR]
[TR]
[TD]2130[/TD]
[TD]6[/TD]
[TD]Convulsed; Drowsiness; Severe lip-twitching; epigastric aura; twitch L arm; amnesia[/TD]
[/TR]
[TR]
[TD]1620[/TD]
[TD]8[/TD]
[TD]Convulsed; Vertigo and severe lip twitching; epigastric aura; spasmodic respiration;[/TD]
[/TR]
[TR]
[TD]1115[/TD]
[TD]4[/TD]
[TD]Inspiratory predominance; lip-twitching and syncope; Nausea and confusion[/TD]
[/TR]
[TR]
[TD]610[/TD]
[TD]6[/TD]
[TD]Dazed and lip-twitching; paraesthesiae; vertigo; "Diaphragmatic spasm"; Severe nausea[/TD]
[/TR]
[TR]
[TD][/TD]
[TD][/TD]
[TD] [/TD]
[/TR]
[/TABLE]
The PPO2 in the described by the OP was low (1.28ppO2), which would generally/simplistically discourage agreement that his symptoms were, indeed, an O2 toxicity related event. However, the symptoms described do fit the model for O2 toxicity. The OP also describes maintaining a regular frequency of nitrox diving - which leads to concerns that their NOAA CNS Daily Limits may have been approached, or exceeded, over multiple dives/days - which is believed to raise susceptibility to oxygen toxicity onset.
Article on CNS Daily Limits by Doppler: http://www.scubaboard.com/forums/content/357-daily-limits-cns-oxygen-toxicity.html
The issue of multiple, over single, exposure also needs to be accounted for - especially as the OP described repetitive, deep nitrox dives over a multi-day period. I'm not suggesting that the OP might have exceeded these limits (without knowing precise schedules for past diving), but it can be seen that there is more to consider than simply the specific PPO2 and exposure time for the single dive where symptoms may have been symptomatic...
[TABLE="class: text"]
[TR]
[TD="colspan: 3"]Normal Operations[/TD]
[/TR]
[TR]
[TD]Oxygen Partial Pressure (ata)
1.6
1.5
1.4
1.3
1.2
1.1
1.0
0.9
0.8
0.7
0.6[/TD]
[TD]Maximum Duration
for a Single Exposure (min.)
45
120
150
180
210
240
300
360
450
570
720[/TD]
[TD]Maximum Total Duration
for any 24-Hour Day (min.)
150
180
180
210
240
270
300
360
450
570
720
[/TD]
[/TR]
[/TABLE]
Also see: NOAA CNA Percentage Oxygen Exposure Table.
Other factors which effect susceptibility (referred to as "oxygen tolerance") are:
- There is a large individual variation in susceptibility and time of onset to symptoms.
- Compared to dry exposures, immersion decreases oxygen tolerance a great deal, decreasing exposure times up to a factor of 4 or 5.
- Exercise decreases oxygen tolerance a lot, compared to rest - believed issues with CO2 retention and tox susceptibility.
- Diving in very cold (<49°F / 9°C) or very warm (>88°F / 31°C) water seems to decrease oxygen tolerance.
Read: DAN discusses the dangers of oxygen toxicity when using nitrox as a breathing gas, By Dr. E.D. Thalmann
In sum, the issues of individual oxygen tolerance, exposure time and %24hr exposure are all factors that could point towards this being an O2 Toxicity event, even though the maximum PPO2 for the symptomatic dive was safely below the maximum threshold.
It would be a rare occurrence - but O2 toxicity (and DCS) is not an exact science, nor is safety/immunity guaranteed simply by following the standard guidelines and remaining within 'advised' thresholds. As such, it is absolutely wrong to assume that this cannot be O2 toxicity, simply due to PPO2/Time exposure on a single dive, without recognition of many other, potentially contributing, factors and an understanding of the variances involved.
CON - convulsions, short tense muscle contractions (tonic); followed by rapid spasms/convulsive jerking (clonic)
V - visual disturbances, especially tunnel vision or blurred vision
E - ear ringing, such as tinnitus
N - nausea, vertigo and dysphoria ("just didn't feel right")
T - tingling, muscle twitching and cramping
I - irritability, personality changes and anxiety
D- dizziness, confusion and decreased consiousness
Illustration of symptom onset, from study:
Oxygen Poisoning at 90 ft (27 m) in the Dry in 36 Subjects in Order of Performance
by K W Donald (1947). px"Oxygen Poisoning in Man: Part I". British Medical Journal
[TABLE="width: 500"]
[TR]
[TD]Exposure (mins.)[/TD]
[TD]Num. of Subjects[/TD]
[TD]Symptoms[/TD]
[/TR]
[TR]
[TD]96[/TD]
[TD] 1[/TD]
[TD]Prolonged dazzle; severe spasmodic vomiting[/TD]
[/TR]
[TR]
[TD]6069[/TD]
[TD]3[/TD]
[TD]Severe lip-twitching; Euphoria; Nausea and vertigo; arm twitch[/TD]
[/TR]
[TR]
[TD]50554[/TD]
[TD]4[/TD]
[TD]Severe lip-twitching; Dazzle; Blubbering of lips; fell asleep; Dazed[/TD]
[/TR]
[TR]
[TD]31354[/TD]
[TD]4[/TD]
[TD]Nausea, vertigo, lip-twitching; Convulsed[/TD]
[/TR]
[TR]
[TD]2130[/TD]
[TD]6[/TD]
[TD]Convulsed; Drowsiness; Severe lip-twitching; epigastric aura; twitch L arm; amnesia[/TD]
[/TR]
[TR]
[TD]1620[/TD]
[TD]8[/TD]
[TD]Convulsed; Vertigo and severe lip twitching; epigastric aura; spasmodic respiration;[/TD]
[/TR]
[TR]
[TD]1115[/TD]
[TD]4[/TD]
[TD]Inspiratory predominance; lip-twitching and syncope; Nausea and confusion[/TD]
[/TR]
[TR]
[TD]610[/TD]
[TD]6[/TD]
[TD]Dazed and lip-twitching; paraesthesiae; vertigo; "Diaphragmatic spasm"; Severe nausea[/TD]
[/TR]
[TR]
[TD][/TD]
[TD][/TD]
[TD] [/TD]
[/TR]
[/TABLE]
The PPO2 in the described by the OP was low (1.28ppO2), which would generally/simplistically discourage agreement that his symptoms were, indeed, an O2 toxicity related event. However, the symptoms described do fit the model for O2 toxicity. The OP also describes maintaining a regular frequency of nitrox diving - which leads to concerns that their NOAA CNS Daily Limits may have been approached, or exceeded, over multiple dives/days - which is believed to raise susceptibility to oxygen toxicity onset.
Article on CNS Daily Limits by Doppler: http://www.scubaboard.com/forums/content/357-daily-limits-cns-oxygen-toxicity.html
The issue of multiple, over single, exposure also needs to be accounted for - especially as the OP described repetitive, deep nitrox dives over a multi-day period. I'm not suggesting that the OP might have exceeded these limits (without knowing precise schedules for past diving), but it can be seen that there is more to consider than simply the specific PPO2 and exposure time for the single dive where symptoms may have been symptomatic...
[TABLE="class: text"]
[TR]
[TD="colspan: 3"]Normal Operations[/TD]
[/TR]
[TR]
[TD]Oxygen Partial Pressure (ata)
1.6
1.5
1.4
1.3
1.2
1.1
1.0
0.9
0.8
0.7
0.6[/TD]
[TD]Maximum Duration
for a Single Exposure (min.)
45
120
150
180
210
240
300
360
450
570
720[/TD]
[TD]Maximum Total Duration
for any 24-Hour Day (min.)
150
180
180
210
240
270
300
360
450
570
720
[/TD]
[/TR]
[/TABLE]
Also see: NOAA CNA Percentage Oxygen Exposure Table.
Other factors which effect susceptibility (referred to as "oxygen tolerance") are:
- There is a large individual variation in susceptibility and time of onset to symptoms.
- Compared to dry exposures, immersion decreases oxygen tolerance a great deal, decreasing exposure times up to a factor of 4 or 5.
- Exercise decreases oxygen tolerance a lot, compared to rest - believed issues with CO2 retention and tox susceptibility.
- Diving in very cold (<49°F / 9°C) or very warm (>88°F / 31°C) water seems to decrease oxygen tolerance.
Read: DAN discusses the dangers of oxygen toxicity when using nitrox as a breathing gas, By Dr. E.D. Thalmann
In sum, the issues of individual oxygen tolerance, exposure time and %24hr exposure are all factors that could point towards this being an O2 Toxicity event, even though the maximum PPO2 for the symptomatic dive was safely below the maximum threshold.
It would be a rare occurrence - but O2 toxicity (and DCS) is not an exact science, nor is safety/immunity guaranteed simply by following the standard guidelines and remaining within 'advised' thresholds. As such, it is absolutely wrong to assume that this cannot be O2 toxicity, simply due to PPO2/Time exposure on a single dive, without recognition of many other, potentially contributing, factors and an understanding of the variances involved.
Last edited: