It's weight. The system becomes much more expensive and complex because it's so much heavier and denser. This is from an excellent 2019 article in Smithsonian magazine A Deep Dive Into the Plans to Take Tourists to the 'Titanic'How much more expensive would it have been to make the carbon fiber part out of titanium like the endcaps? Or weight becomes issue?
"The weight of steel and titanium subs makes them expensive to transport on land and requires large ships, outfitted with cranes, to launch at sea. Because of their heft, traditional subs tend to require bulky, syntactic foam flotation blocks to maintain neutral buoyancy, which is crucial for maneuverability. Titan, by contrast, is much cheaper to transport and launch, and without the foam is nimbler in the water."