I'm far from being an experienced diver, but I probably have some more experience with chemistry and gases. I feel the whole "O2 Clean" discussion is 80% trying to sell overpriced equipment to divers and manufacturers cushioning their profit margins, 20% facts and figures.
You'll be totally alright using the same regulator for O2 and EAN 50. You must indeed have some precautions handling and breathing oxygen, but oxygen is no hydrogen and no nitroglycerin either.
I don't understand this oxygen mystique in the diving world. I know there's wreckless people in every walk of life, and you can do silly things when handling oxygen, but still.
Probably the most dangerous part of diving in general and breathing oxygen in particular is how many dive shops mishandle their oxygen reserves, with many of them (SE Asia) storing their oxygen bottles in a warm, poorly ventilated compressor room. Probably for fear of someone stealing their bottles.
Should there be a leak in one of the bottles and a spark from the compressor electrics, it would make for instant fireworks and a few casualties. I try to stay as far away from those compressor rooms as I can. Same goes for oxygen storage in liveaboards in Asia. Accidents waiting to happen everywhere.