No. The systems is exactly the same. If the preflash gets no return you get a full dump. Fiber optics are multimodal and travel fast wired cables are connected to a terminal that only does one thing. The optical connection is always superior for any transmission you do to copper or any wire. What changes is the quality of the P-TTL of the camera and the ability of the strobe to emulate the internal flash. As I have tested the YS-01 and the inon Z240 with the RX100 I can tell you the two strobes behave differently. The inon sends a much stronger preflash signal when I connected the two strobes the YS-01 would barely fire as a consequEnce. Connecting a single strobe results in perfect exposures with the inon and many overexposed pictures with the Ys01 in virtue of the lack of controls. I had plenty of overexposed pictures with the panasonic LX7 with the YS 01 in macro too. When you are really close you end up in a situation that even little is too much, the inon strobes have a ttl low setting the sea and sea don't so you need to play with the dimmer. At some point you might as well shoot manual